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The best ergonomic wireless mouse: What are your options?

Getting wrist pains and strain?

Published onMarch 12, 2022

Logitech MX Vertical

There’s a mouse for everyone: gamers, office workers, multi-taskers, etc. Ergonomic mice aren’t as good-looking as the competition, but they do better where it matters. Ergonomic mice are designed to be much more comfortable for long work sessions, and today we’re here to help you find the best ergonomic wireless mouse around.

Why should you get an ergonomic mouse?

Working on a computer all day is an easy way to end up with wrist pain and possible long-term health issues. Part of the problem comes from the unnatural position that most computer mice force on your hand. If you’re experiencing discomfort, you need to learn more about using your mouse correctly.

This is especially important considering there can be severe consequences from long-term mouse use. The National Center for Biotechnology Information has proven long-term mouse use can cause median nerve entrapment neuropathy at the wrist. It can also cause aches and fatigue in the short term. What can we do about this?

Ergonomic mice help keep your wrist in a more natural position, which is essential to keep you working hard. It forces your hand into a position closer to a handshake, which is a much more natural position that will help in the long (and short) term. As a result, many of these ergonomic mice sport unique designs. Additionally, ergonomic mice make you move your arm instead of just your wrist. This means the strain is spread across your whole arm instead of concentrating on your wrist. You may have to get used to the shape and the look, but your wrist will thank you.

Getting the right mouse helps, but using your mouse correctly and keeping a good posture is more critical. Here are some tips you should practice whenever using your mouse.

  • Don’t firmly grip your mouse. Hold it and move it loosely.
  • Don’t rest your mouse or forearm on the same surface as the mouse. Try to let your wrist/arm float above, instead.
  • Make sure your elbow is bent as close to 90 degrees as possible.
  • Take breaks often.

We should mention that, while all these tips and ergonomic mice help, nothing guarantees you won’t be affected by frequent mouse use. It simply reduces the chances of any issues. Let’s help you improve your chances of a healthy work-life with the best ergonomic wireless mice.

More: How to set up a home office

The best ergonomic mice

Editor’s note: We will update our list of the best ergonomic mice as new mice launch.

Logitech MX Vertical

Logitech MX Vertical

Vertical mice are nothing new, but the Logitech MX Vertical is arguably the best in terms of comfort, features, and brand trust. According to Logitech, the MX Vertical offers up to a 10% reduction in muscle strain due to the mouse’s tilt angle of 57 degrees.

The MX Vertical also offers several distinct features, apart from solid ergonomics. The mouse provides up to four months of battery life and can be recharged through the USB-C port. Also, the MX Vertical features wired and wireless options over Bluetooth and USB, respectively.

It’s also a competent mouse, featuring a 4,000 DPI design, Logitech Flow support for using it with multiple machines at once, and amazing 4-month battery life.

Logitech MX Ergo

Logitech MX Ergo

The Logitech MX Ergo doesn’t win points for being a vertical mouse since it isn’t. Instead, the MX Ergo wins points for its unique design. You’ll notice the massive trackball, which lets you move the cursor with your thumb. Arguably more important is the metallic plate attached to the MX Ergo’s body that enables you to tilt the mouse up to 20 degrees to the right. This makes it a semi-vertical mouse.

Related: 10 tips for working remotely

The trackball and metallic plate combine for a peak ergonomic and comfortable mouse experience. If you’re concerned about the trackball’s speed, the Precision Mode button next to it slows the tracking to a crawl.

Microsoft Sculpt

Microsoft Sculpt

Let’s start by saying there are better ergonomic wireless mice on this list, but this is an excellent option if you want to stick with an official Microsoft product. The Microsoft Sculpt still has an ergonomic design that angles your hand and provides better comfort.

A dedicated Windows button makes it easy to access the start menu, and battery life is estimated at 12 months. It uses a 2.4GHz dongle, so this might not be the best option if you need Bluetooth compatibility.

Autley Wireless Vertical Mouse

Autley Wireless Vertical Mouse

If you want an inexpensive option for a vertical mouse, the Autley Wireless Vertical Mouse should be at the top of your list.

It features 800, 1200, and 1600DPI settings, and the vertical mouse also features silent left and right clicks. Also available are a DPI button below the scroll wheel, forward and back buttons, and a strip of light below the thumb rest area.

Autley’s mouse doesn’t feature Bluetooth, but there’s support for a 2.4GHz wireless connection with the included USB adapter. Finally, the mouse is one of a select few at its price point to have a rechargeable battery.

Logitech Ergo M575 Wireless Trackball

Logitech Ergo M575 Wireless Trackball

Logitech is one of the biggest brands, and they arguably make some of the best ergonomic wireless mice, but they can get pricey. If you’re on a tight budget and still want a Logitech ergonomic wireless mouse, then the Logitech Ergo M575 Wireless Trackball is the one for you.

It’s not as angled as other options, but it’s still comfortable and features a trackball, which can help you avoid moving your hand around. It features a 2,000DPI sensor and 2.4GHz support. There is no Bluetooth, but that’s usually a feature that goes out the window whenever you start looking at more affordable options.

Kensington Pro Fit Ergo Vertical Wireless Trackball

Kensington Pro Fit Ergo Vertical Wireless Trackball 1 ergonomic wireless mouse

Kensington is known mainly for its storage products and other PC devices in the computer world. It also knows how to make great ergonomic mice, though, and its best one is a great option. The 60-degree tilt is among the best, and it includes a great trackball you can use to avoid hand movement.

Also: Top productivity gadgets for your office

Additionally, the Kensington Pro Fit Ergo supports a 2.4GHz connection and Bluetooth with up to two devices. The 18-month battery life is also stunning. The price is not nearly as high as other ergonomic wireless mice with the same build and features.

Anker Wireless Vertical Ergonomic Mouse

Anker Wireless Vertical Ergonomic Mouse

Anker’s best known for its power banks, but the company also makes mice. Enter the Anker Wireless Vertical Ergonomic Mouse, a clumsy name for what promises to be a very comfortable mouse to use. Featuring 800, 1200, and 1600DPI settings, Anker’s vertical mouse features your standard array of right, left, DPI switch, forward, and back buttons. There’s also a scroll wheel. The DPI switch button is above the forward and back buttons near the thumb rest.

There’s no Bluetooth support, though wireless support is still here over the USB adapter’s 2.4GHz connection. There’s also no rechargeable battery, so you’ll have to provide your own set of AAA batteries.

iClever Ergonomic Mouse

iClever Ergonomic Mouse

One issue with ergonomic mice is that they can be pretty ugly. Those who care about looks will find the iClever Ergonomic Wireless Mouse one of the best options. It has a fascinating, futuristic design that will turn some heads.

Also read: 10 best standing desk options available

It’s not lackluster either. You can pick between 800DPI, 1,200DPI, and 1,800DPI. It comes with a wireless receiver and even features super quiet buttons for office use. It needs batteries and has none, but it’s a pretty affordable mouse, so sacrifices must be made somewhere.

Evoluent VerticalMouse D

Evoluent VerticalMouse D ergonomic wireless mouse

The Evoluent VerticalMouse D is also peculiar. When placed on a table, the VerticalMouse almost sits perpendicular due to the extreme vertical position. It keeps your fingers firmly on one side with your thumb on the other thanks to an additional center button and the scroll wheel, left-, and right-click buttons. That means you’ll want to take some time to learn how to use the mouse.

With the Evoluent Mouse Manager, you can configure all VerticalMouse’s buttons. You can also change how the buttons work in specific applications, a nice inclusion for the productivity-focused.

Contour Design Unimouse

Contour Design Unimouse ergonomic wireless mouse

The Contour Design Unimouse is one of the most versatile ergonomic wireless mice. You can adjust the angle and extend the thumb rest for a wider grip. Additionally, there are both right-handed and left-handed versions.

You can pick between ten cursor speeds and get six programmable buttons. There’s no Bluetooth here, but you can still enjoy a 2.4GHz connection with a 25-foot range.


Q: What’s the right angle for an ergonomic mouse?
A: According to mouse maker Goldtouch, your mouse should be angled at 20—90 degrees. The more vertical, the better, though.

Q: Do I need a wireless mouse?
A: Not necessarily, but cables can be annoying and make a mouse slightly harder to move around. Not to mention portability will be affected, so you might not want to take your mouse on trips or to coffee shops. A wireless mouse is easier to carry, which will help you enjoy the benefits of ergonomic mice more often.

Q: How important is a trackball?
A: Some see this as a gimmick, but using a trackball can help improve comfort and wrist health significantly. You’re not using arm, hand, or wrist force when using a trackball, as you’re not technically moving the mouse.

Now that you have the right tools, you might also want to look at our guide for focusing on work when working from home. You might also want to separate your workspace adequately.

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