The 10″ tablets are usually hard to hold with one hand, because of the (still) fairly bulky weight (600+ grams, ideal weight for one-handed use is around half of that), and it’s one of the reasons why people prefer 7″ tablets like the Nexus 7. It’s just that some might find the screen size too small, which is why it’s important to come up with innovations. Sony, in response, has tried to improve the usability of a 9″-10″ tablet.
Unfortunately, the Sony Tablet S arrived too late in the market, with an old version of Honeycomb, with Tegra 2, and at a fairly high price ($600). This ended its life cycle almost immediately. But it seems Sony may be willing to give it another try soon, with the second generation of the Sony Tablet S, that will launch almost exactly a year after the original. The tablet’s successor, with the model number SGPT1211 has just won FCC approval, which means it won’t be long before we see it in the market.
This means that it should have a powerful CPU and GPU as well, but it’s hard to estimate what they will use. It could either be a Tegra 3, or if they release it later, a quad core Snapdragon S4 Pro, with an Adreno 320 GPU. I would still bet on Tegra 3, though. They may want to take advantage of the Tegra Zone as well, if they want to promote this as a gaming device.